The practical approach of Immuno histochemical markers in Solitary Fibrous Tumour (SFT)

A solitary fibrous tumour is an unknown neoplasm that fibroblastic in nature. It causes diagnostic difficulty due to its unexpected Immunophenotypic appearance as well wide histologic appearance, but most of the time it accurately diagnosed histological characteristics and strong positivity CD34 expression.SFT known occur almost all parts body including meninges skin. This a slow-growing can be successfully treated by complete excision; malignant counterpart SFT rare. The important reliable positive markers are CD34, CD99, BCL2. There consistently negative this tumor well, used according location, such EMA&S100.Although majority frequent expression, spectrum occurrence immunophenotype might offer difficulties. Research findings shows that, meninges, orbit, upper respiratory tract, salivary glands, thyroid, peritoneum, liver, retroperitoneum, pelvis, adrenal gland, kidney, urinary bladder, vagina, spinal cord, skin, periosteum, soft tissues have been form neoplasm.